Increasing the dose of inhaled corticosteroid when asthma deteriorates--does it prevent severe exacerbations?
نویسنده
چکیده
منابع مشابه
Doubling the dose of inhaled corticosteroid to prevent asthma exacerbations: randomised controlled trial.
BACKGROUND Asthma self-management plans that include doubling the dose of inhaled corticosteroid when the condition deteriorates improve asthma control. Whether doubling the dose of corticosteroid in isolation is effective is unknown. We undertook a randomised controlled trial to investigate the effects of doubling the dose of inhaled corticosteriods when asthma deteriorates. METHODS 390 indi...
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OBJECTIVE To determine the comparative effectiveness and safety of current maintenance strategies in preventing exacerbations of asthma. DESIGN Systematic review and network meta-analysis using Bayesian statistics. DATA SOURCES Cochrane systematic reviews on chronic asthma, complemented by an updated search when appropriate. ELIGIBILITY CRITERIA TRIALS OF Adults with asthma randomised to ma...
متن کاملCorticosteroid therapy and chronic obstructive pulmonary disease.
Chronic obstructive pulmonary disease is characterized in part by a chronic inflammatory state in the airways (largely from chronic noxious stimuli such as tobacco smoke), punctuated with acute inflammatory exacerbations, which are often infectious. Although pathologically and biochemically different from the inflammation of asthma, the chronic inflammation of chronic obstructive pulmonary dise...
متن کاملFourFold Asthma Study (FAST): a study protocol for a randomised controlled trial evaluating the clinical cost-effectiveness of temporarily quadrupling the dose of inhaled steroid to prevent asthma exacerbations
BACKGROUND Asthma is one of the commonest chronic diseases in the UK. Acute exacerbations of asthma are unpredictable, disruptive and frightening. They cause considerable morbidity and account for a large component of the health service costs of asthma. The widespread use of an asthma self-management plan, designed to encourage disease monitoring and timely intervention, can reduce exacerbation...
متن کاملDual components of optimal asthma therapy: scientific and clinical rationale for the use of long-acting beta-agonists with inhaled corticosteroids.
The authors describe the scientific rationale for using an inhaled corticosteroid with an inhaled long-acting beta 2-agonist. They discuss the clinical trials demonstrating that using an inhaled corticosteroid with an inhaled long-acting beta 2-agonist provides greater overall asthma control compared with increasing the dose of inhaled corticosteroid. In addition, they review the clinical trial...
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ورودعنوان ژورنال:
- Polskie Archiwum Medycyny Wewnetrznej
دوره 120 3 شماره
صفحات -
تاریخ انتشار 2010